Monday, 27th August The Annual Scientific Meeting of the Endocrine Society of Australia and the Society for Reproductive Biology 2012

• Looking after the maternal legacy: Mitochondrial dynamics and function in the oocyte to embryo transition. - John Carroll

• Long-term persistence of hormonal adaptations to weight loss - Priya Sumithran

• Silencing of Ghrelin Receptor Expression Inhibits Endometrial Cancer Cell Growth in vitro and in vivo - Jenny Nga Ting Fung
• The Decline in Pulsatile Growth Hormone Secretion throughout Early Adulthood in Mice is Exacerbated by Dietary Induced Weight Gain - Lili Huang
• Interaction between hypoxia and mutations in SDH subunit genes associated with phaeochromocytoma/paragangliomas - Venessa HM Tsang
• SLIRP represses retinoic acid and Notch signalling in colorectal cancer and is a good prognostic factor - Patrick Candy
• Role of androgens via AR in PTEN inactivation induced uterine pathology. - Jaesung P Choi
• Hypoxia inducible factor-1α increases promoter II-driven aromatase expression in postmenopausal breast cancer - Nirukshi Samarajeewa

• Male Infertility and Assisted Reproduction   - Robert I McLachlan
• Successes today and tomorrow - Michael Chapman
• The role of molecular chaperones in regulating human sperm-egg recognition - Brett Nixon

• Glucocorticoid excess in pregnancy impairs placental haemodynamics with novel implications for fetal cardiac function. - Caitlin S Wyrwoll
• Ly6e is essential for normal placental labyrinth formation - David G Simmons
• Embryo-maternal interactions critical for IVF success - Carly Cuman
• Gene expression and targeted RNA sequencing in genomic regions associated with increased endometriosis risk - Grant W Montgomery
• Endometrial Expression of Kallikrein 6 is Linked with Infertility - Tracey A Edgell
• Are uterine fibroids really clonal? - Marina Zaitseva

Professor Karen Lam - Obesity, Diabetes & Cancers

• AR-Cell Cycle Crosstalk:  impact on cancer progression & therapeutic response - Karen Knudsen

• ESA-Antibiotic Resistance, Guidelines and Stewardship - David FM Looke

• SLC13A4 Sulfate Transporter Is Critical For Fetal Development And Survival - Joanna Rakoczy
• Pregnancy alters body composition, vitamin D and calcium levels in mice - Jessica Laurence
• Alterations in the maternal renin angiotensin system (RAS) in women who deliver preterm or small for gestational age babies - Shane D Sykes
• Quantitative allele-specific expression analysis of imprinted genes in human placenta reveals plasticity in imprinting of H19 and biallelic expression of IGF2R across gestation - Sam Buckberry
• Placental specific mRNA in the maternal circulation are globally dysregulated in pregnancies complicated by fetal growth restriction - Clare L Whitehead
• The production of sFlt-1 splice variants is regulated by jumonji domain containing protein 6 (Jmjd6) in the placenta. - Kirsten R Palmer

• Musashi-2: an essential regulator of DNA recombination and repair - Eileen A McLaughlin
• Involvement of an uncharacterised microtubule-severing enzyme, KATNAL2, in spermatogenesis - Liza O'Donnell
• Meiosis does not require a fully functional blood-testis barrier - Jenna T Haverfield
• LRGUK-1 has a critical role in the formation of the acrosome, manchette and tail axoneme - Kathleen DeBoer
• Identifying Biomarkers of Chronic Acrylamide Exposure in the Male Germ Line. - Belinda J Nixon
• Testicular spermatogenic cells activate inflammatory signalling pathways linked to the Toll-like receptors - Julia M Young

• Iron Chelation Prevents Obesity by Increasing Hypothalamic Hypoxia-Inducible Factor-1α, Metabolic Rate and Adipose Tissue Browning - Natasha Deters
• Intrauterine growth restriction induces central fat in the adult sheep - Hong Liu
• Vitamin D Exerts Anti-proliferative and Modulatory effects in the Differentiation of Skeletal Muscle Cells  - Christian M Girgis
• Establishing regularity: Assessing pulsatile GH secretion in early-pubertal versus early-adult mice. - Kevin W Lee
• Pulsatile Growth Hormone Secretion is Inversely Correlated to Adiposity and Circulating Levels of Leptin in Mice - T Y Xie
• RF-amide Related Peptide-3 (RFRP-3) Neurons do not Mediate Leptin Actions - Anan Harbid

• Circadian rhythms and the regulation of mood disorders. - Tamara J. Varcoe
• Fat and the brain - interactions between obesity, appetite and mood - Gilberto Paz-Filho
• Low prolactin during early pregnancy impairs maternal behaviour postpartum, and delays the onset of puberty in female offspring. - Caroline M Larsen
• Prenatal programming of stress dysregulation: epigenetic and placental contributions - Tracy Bale

• Regulated Wnt/beta-catenin signalling is intrinsically required for adult spermatogenesis - Genevieve E Kerr
• The Anaphase-Promoting Complex activator Fizzy-Related-1 (FZR1) is essential for the mitotic divisions of early mammalian embryos but not for the completion of female meiosis - Michelle Kay Yi Seah
• Growth Hormone's mode of action upregulates FSH, LH and BMP receptor expression on granulosa cells from IVF patients. - Sheena Regan
• Melatonin prevents oocyte aging in the mouse and extends the window for optimal fertilization in vitro - Tessa Lord
• CDC14B role in male meiosis     - S. M. R. Oliveira
• Capacitation in the presence of methyl -β- cyclodextrin results in lipid raft migration and enhanced zp-binding ability of stallion sperm in vitro - Elizabeth G Bromfield
• The Presence of a truncated DNA base excision repair pathway in human spermatozoa, mediated by OGG1 - Tegan B Smith
• RAB-Like 2 (RABL2) function in male fertility, intra-flagella transport and sperm tail assembly - Jennifer Lo

• Acute effect of calcium supplementation on cardiovascular function - Morton G Burt
•  Trimester Specific Reference Intervals for Thyroid Function - Elif I Ekinci
• Effects of Raloxifene and Oestrogen on Bioactive IGF-I in Healthy and GH-Deficient Women - Vita Birzniece
• The relationship between TSH and free T4 is not log-linear and differs between genders and age groups - Karen Rothacker
• Nadolol impairs pancreatic glucose sensitivity in patients with liver cirrhosis - Wai Gin Lee
• Higher free thyroxine levels predict increased incidence of dementia in older men. The Health In Men Study. - Bu B Yeap
• The role of activin A and follistatin in the acute phase and reperfusion responses during lung transplantation - David M De Kretser
• Salivary alpha amylase (sAA) response to psychological stress in lean and overweight/obese men - Sisitha U Jayasinghe

• A subset of tumour cells in primary localized prostate cancers are resistant to androgen deprivation (castrate resistant): Implications for treatment strategies. - Gail Risbridger
• PGE2 downregulates tumour suppressor p53 and enhances aromatase expression in human breast adipose stromal cells - Lixian Wang
• The use of Long Terminal Repeats as Androgen-Responsive Enhancers in the PSA-Kallikrein Locus - Judith A Clements
• Prostate epithelial AR inactivation in mice prevents experimental prostate cancer progression induced reduction in intraprostatic DHT - Win Myat Theingi
• A novel steroid hormone receptor coactivator associated with tamoxifen resistance - Colin Clyne
• Androgens Modify Skin Formation and DMBA-Induced Pathology in Mice - Tegan Ryan
• Generation of a doxycycline-inducible mammary specific Liver Receptor Homolog-1 knock-in mouse - Kyren A Lazarus
• Identification of novel LRH-1 target genes in breast cancer cells - Zhe Zhao

• Maternal glucocorticoid exposure alters placental expression of the renin-angiotensin system - James SM Cuffe
• Decreased uterine artery compliance in pregnant relaxin deficient mice is reversed with relaxin treatment - Jonathan H Gooi
• Sulfate: an obligate nutrient for fetal development in human and animal gestation. - Paul A Dawson
• Combination gefitinib and methotrexate to medically treat ectopic pregnancy: a phase I clinical trial. - Monika M Skubisz
• PAPP-A2 in the Pathogenesis of Pre-eclampsia - Kathleen R Macintire
• Sexually dimorphic placental development throughout gestation in the spiny mouse - Hayley Dickinson
• Calcium prevents endothelial cell activation induced by two separate activators, necrotic trophoblastic debris or IL-6 - Qi Chen
• Vitamin D binding protein as a predictor of human labour - Stella Liong

• DNA binding cofactors contribute to plasticity of progesterone receptor cistromes - J Dinny Graham
• Cure rates after single dose radioactive iodine treatment for thyrotoxicosis are lower for Maori than Caucasians - Jade Tamatea
• Exploring the complex roles of oestrogen in endometrial tumorigenesis in 3D cell culture system - Chao Lin
• Follicle-stimulating hormone stimulates the tumourigenic behavior of breast cancer cells in vitro. - Eliza J Whiteside
• De novo steroidogenesis in prostate cancer cells is increased by insulin-like growth factor II. - Adrian Herington
• KLK4-initiated protease cleavage of the receptor tyrosine kinase EphB4 at the surface of prostate cancer cells - a possible mechanism for regulation of EphB4 signaling. - Sally-Anne Stephenson

• Expression of Somatostatin within the Hypothalamus throughout the Alteration in Pulsatile Growth Hormone Secretion in the Early-Adult Mouse - Hwee Y Tan
• Waking cortisol, resilience, but not 5-HTTLPR polymorphisms, predict depression. - Suresh Kumar Athiappan Palanisamy

• Sex Differences in the Role of cAMP Response Element Binding Protein in Gonadotropin-Releasing Hormone Neurons - Andrea Kwakowsky
• Matrix metalloproteinase (MMP) may be required for gonocyte transformation in postnatal l testicular tubules - Ruili Li
• Vitamin D insufficiency is prevalent but does not influence glycaemia in pregnancy - Chris White
• Characterisation of the bioactivity of the naturally occurring Inhibin Proα-peptide. - Kelly L Walton
• Postnatal mRNA Expression of Ten Bone Morphogenetic Protein Family Members in the Developmental Mouse Testis - Ilona M. Ciller
• Non-DNA binding-dependent androgen receptor pathway in fat - Kesha Rana
• Placental mitochondrial dysfunction in pregnancies complicated by asthma - Zainab Ali
• Effect of cortisol and lipopolysaccharide on micro RNA and glucocorticoid receptor expression  - Annette Osei-Kumah
• Toll-Like Receptor activation in preterm neonates: the effect of gestational age and antenatal betamethasone therapy - Natalie Aboustate
• The satiety adipokine Nesfatin-1/NUCB2 is expressed in human term trophoblast and placental mesenchymal stem cells and is increased during oxidative and ER stress - Penny Jeffery
• Overweight, obesity and central obesity in women with polycystic ovary syndrome: A systematic review and meta-analysis - Lisa J Moran

• Effects of in vivo hexarelin treatment on contractility, [Ca2+]i, membrane potential and Ito current in ventricular myocytes from streptozotocin-induced diabetic rats - Xinli Zhang

• Evaluation of post hypophysectomy ACTH sufficiency:  early and week 6 overnight metyrapone test compared with short synacthen test and insulin hypoglycaemia test. - Zara Weedon
• Does weight affect serum cortisol levels? - Kalani Kahapola Arachchige
• Cortisol Conundrum: Caution on 550 nmol/L cut-off for Synacthen Stimulation Tests. Time to adopt method-specific diagnostic cut-offs! - Ee Mun Lim
• Interferences in testosterone assays - can LCMS be affected?? - Afsana Habib
• The Rise and Rise of Vitamin D Testing in Australia: Lessons for other nations and an international need to establish test guidelines - Kellie Bilinski
• Development of a Sensitive Enzyme-linked Immunosorbent Assay (ELISA) for the Determination of Pulsatile Luteinizing Hormone Secretion in Mice - Ying Wan
• Validation and application of an ultra-sensitive liquid chromatography (LC)-tandem mass spectrometry (MS) assay to measure androgens and estrogen in human urine.  - Gurmeet Kaur Surindar Singh

• Management Of Primary Hyperparathyroidism At Eastern Health - Negar Naderpoor
• Identification of subjects with glucocorticoid-induced hyperglycaemia while on high dose glucocorticoids as part of chemotherapy protocol - Cross Sectional study - Soulmaz Shorakae
• Testosterone Levels in Men with Minimal Trauma Fracture - Mathis Grossmann
• The frequency of osteoporosis testing in females aged 45 to 74 did not rise despite a marked increase in testing for vitamin D deficiency: a ten year observational study. - Steven Boyages
• Retrospective study: Management of the initial hypoglycaemic event in hospitalised patients and its impact. - Dilantha De Alwis
• Free and Total Cortisol Measured by Immunoassay and Mass-spectrometry Following ACTH_1-24 Stimulation in the Assessment of Pituitary Patients - Matthew P Doogue
• The MAPrc Women's Mental Health Clinic - Roisin Worsley

• Comparison of Outcomes after Laparoscopic vs Posterior Retroperitoneoscopic Adrenalectomy - Miguel S Cabalag
• Amiodarone-induced thyrotoxicosis – do anti-thyroid drugs alone provide adequate treatment? - Nadia Patel

• An adrenal adenoma co-secreting cortisol and aldosterone associated with both a bronchial adenocarcinoma and a papillary thyroid carcinoma. - Clement Lo
• Hypoadrenalism and Acute Neurological disturbances - Peter Davoren
• Induction of spermatogenesis in the setting of panhypopituitarism and prior chemotherapy - Santhi Chalasani
• Autoimmune thyroid disease following alemtuzumab therapy for multiple sclerosis  - Pinar Kozan
• Kallmann syndrome and schizencephaly: concurrent neuron migration defects. - Shannon E McCarthy
• Gestational hypercalcaemia in familial hypocalciuric hypercalcaemia - Rashmi Narayanan
• A rare case of hypercalcaemia with unexpected dual pathology consisting of a sarcoid granuloma within a parathyroid adenoma. - Anne Trinh
• Bilateral adrenal haemorrhage and adrenal crisis in the context of antiphospholipid antibody syndrome. - Shannon E McCarthy
• A rising trend in search requests for vitamin D using Google corresponds to increased test orders for 25-hydroxyvitamin D by practitioners in Australia - Kellie Bilinski
• Corticosteroid-responsive hypercalcemia due to a pthrp-secreting adamantinoma in a patient with severe graves disease - Jason Hockings
• Reversal of rapid bone loss in iatrogenic hyperthyroidism by bisphosphonate treatment and withdrawal of tri-iodothyronine - Nicholas Hockings
• A Case Report Of Suprasellar Mass Lesion Associated With Panhypopituitarism And Diabetes Insipidus - Harish Venugopal
• Diagnostic dilemmas in hyperandrogenism and pregnancy - Harish Venugopal
• Septo-Optic Dysplasia and Liver Cirrhosis – more than just a coincidence? - Moe Thuzar
• Life threatening Pseudohypoaldosteronism - Jennifer Woo
• Adrenal Infiltration presenting as Hypoadrenalism - Algenes Aranha
• A case of life-threatening hypercalcaemia – a parathyroid ‘storm’ - Michelle So
• A Case of Severe Hypercalcaemia Due to Primary Hyperparathyroidism Presenting In Third Trimester Pregnancy - Mor Aik Wee
• Fuel on Fire - Natalie Yap
• A Case of Carcinoid Heart Disease - Maeve E Hutchinson

• Genomic imprinting in the post-natal marsupial - Jessica M Stringer

• Nutrition, testicular mass and sperm viability in the sexually mature male sheep - Yongjuan Guan
• Expression of activin and inhibin in human endocrine tumours - Francesco E Marino

• Nutritional programming of adipose tissue in the tammar wallaby     - Jennifer Hetz
• The STRA8/RA/CYP26B1 Pathway And The Control Of Meiosis In Marsupials - Danielle Hickford

• Stimulating lipid metabolism during porcine oocyte maturation: effect of l-carnitine in the absence of pyruvate and lactate - Jenna L Lowe
• Effect of pH buffer composition on the maintenance of porcine embryo viability during extended out-of-incubator culture - Louise K Bartolac
• Mouse blastocysts produce glutamine from glutamate in the presence of ammonium, but consume glutamine under oxidative stress - Petra L Wale
• In vivo development of the pre-implantation spiny mouse embryo - Hayley Dickinson
• Persistence of Expression of both 5´-methyl Cytosine and 5´-hydroxymethyl Cytosine within the Genome During Zygotic Maturation in the Mouse - Yan Li
• The Effect of Culture on Covalent Modifications to Histone 3 during Maturation of the Mouse Zygote - Charlotte M Rollo

• Development of a mouse model for human polycystic ovary syndrome - Linda J Middleton
• Postnatal peripheral inflammatory challenge alters expression of ovarian signalling pathway - implications for impaired reproductive development.   - Luba Sominsky
• The Role of Bone Morphogenetic Protein Receptor 1B (BMPR-1B) in Mouse Ovarian Follicular Development - Ibtisam AL-ali

• Effects of Dietary Omega-3 Fatty Acids on Oxidative and Inflammatory Status of the Rat Placenta - Megan L Jones
• Selenium Supplementation Protects Trophoblast Cells from Mitochondrial Oxidative Stress - Alisha Khera
• Periconceptional ethanol consumption increase glucose concentrations in pregnant dams and alters fetal and placental growth - Emelie Gardebjer
• DNA methylation associated with induction of CRH gene expression in trophoblast cells - Xin Pan
• The ageing placenta and still birth - Kaushik Maiti
• DNA methylation of progesterone receptor isoforms in term human myometrium. - Sze Yee Chai

• Immunolocalisation of FMR1NB in bull sperm and testis - Keren Byrne
• Oxidative phosphorylation is essential for stallion sperm motility. - Zamira Gibb
• Viability of rabbit spermatozoa stored in different extenders at 5⁰C or 15⁰C for up to 96 hours - Roslyn Bathgate
• Epigallocatechin gallate: friend or foe of stallion spermatozoa? - Sarah R Lambourne
• Oxidative stress and telomere length in human spermatozoa - Matthew S Jobling
• DNA damage in lymphocytes and lifestyle factors are associated with sperm DNA damage - Dylan McCullough

• The hepatocyte growth factor system in menstruation and post-menstrual endometrial repair - L A Salamonsen
• MMP-17: a negative regulator of soluble endoglin production? - Tu'uhevaha J Kaitu'u-Lino
• Corin, a protein involved in spiral arteriole remodelling in mice, is expressed in human endometrium and the villous cytotrophoblast - Laura T Tuohey
• Evidence for the synthesis, secretion and uptake of prorenin in human amnion - Kirsty G Pringle
• Prorenin and the (pro)renin receptor: A potential role in trophoblast spiral artery remodelling - Amanda R Highet
• Enhancing implantation potential in infertile women: a role for exosomes? - Lois A. Salamonsen
• HtrA3 modulating monoclonal antibodies and their potential therapeutic applications - Harmeet Singh
• Proprotein convertase 6 regulation of endometrial receptivity: role in α-Dystroglycan N-terminal shedding - Sophea Heng
• Are rare variants in WNT4 associated with endometriosis risk? - Hien T.T. Luong
• Regulation of seminal fluid-induced leukocyte recruitment by cytokine and chemokine expression in the human cervix after coitus - David J Sharkey
• Alterations in the Adherens Junction During Early Pregnancy in the Rat - Samson Dowland
• Actin Crosslinking Protein Filamin A During Early Pregnancy In The Rat Uterus - Romanthi J Madawala
• Proteomic analysis of diapause and reactivated endometrium of Macropus eugenii (tammar wallaby) using Nano-cHiPLC-MS/MS - Florine Cynthia Martin